Recently, Post-doc Xiyu Li and Professor Wei Li from State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, published their research work in Small (IF: 11.459), entitled "Synergistic Effects of Novel Superparamagnetic/Upconversion HA Material and Ti/ Magnet Implant on Biological Performance and Long-Term in Vivo Tracking”. In this paper, they developed a new type of superparamagnetic/upconversion-generating HA material (HYH-Fe) via a two-step doping method, as well as a specially-designed titanium implant with a built-in magnet to provide a local static magnetic field (SMF) in vivo. The results showed that the combined use of the superparamagnetic HYH-Fe material and SMF could effectively and synergistically promote osteogenesis/osteointegration surrounding the Ti implants. In addition, the HYH-Fe material exhibited distinct advantages in terms of both long-term fluorescence tracking and micro-CT tracking. The new material and tracking strategy in this study provide scientific feasibility and will have important clinical value for long-term tracking and evaluation of the implanted material and the bone repair effect.

Small is a well-known journal in the field of materials science. The journal focuses on the new achievements of nano and micro scale science and technology research. More information about this study can be found at Small (https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201901617).